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2011年4月22日星期五

Popular birth control pills promotes blood clot risk

Among the most popular contraceptive pills available in the Canada - Yaz and Yasmin - carry a higher risk of serious blood clots than some other oral contraceptives, two new studies say.

Studies - both published Thursday in the British Medical Journal Online Edition - show that pills containing a new type of hormone called progestin drospirenone carry up to triple the risk of serious blood clots (known as venous thromboembolisms) on an old generation of pills containing a hormone called levonorgestrel.

Drospirenone is the key ingredient of Yasmin and Yaz, manufactured by Bayer and widely prescribed in the Canada. /

Focused on the drospirenone pills Yaz and Yasmin had global sales of 2 billion dollars in 2009, reports indicated.

Program market from the CBC raised health concerns regarding Yaz and Yasmin in January. Co-Chair Erica Johnson spoke to a number of young women who took the two brands of pills and health problems serious experienced.

More than 4,000 women have taken legal action against Bayer and more than 800 in the Canada joined a class action.

The findings provide evidence that the ancient oral contraceptives "appear to be a safer choice in thromboembolism than preparations containing drospirenone,", explains Dr. Susan Jick, school of medicine, Boston University, who led the research team.

In the first study, the researchers found the risk of a blood clot non-fatal in women using pills drospirenone of was double the risk for women using levonorgestrel containing oral contraceptives.

The study stresses that the overall risk of serious blood clots remains low – even in women taking the pill on the drospirenoane. Incidence rates were 30.8 per 100 000 years of women among the users of drospirenone versus 12.5 by 100 000 years of woman among users of levonorgestrel pills.

The researchers investigated existing U.S. medical claims data to reach their conclusions.

In the second study, researchers have discovered the first non-fatal blood clot risk among women with drospirenone containing oral contraceptives to women who have used the pill levonorgestrel-based almost tripled.

"Prescribe preparations of levonorgestrel risk lower than the choice of first line for women wishing to take an oral contraceptive appear prudent," say the authors.

In a statement, Bayer said Canada "the way the authors applied the methodology of the study reported in these two publications of defects on important show" and maintained that previous studies have shown that Yaz and Yasmin are as safe as other birth control pills.

"In view of the scientific body already large and robust evidence, notice of Bayer, these studies do not change the overall evaluation of the safety of oral contraceptives Bayer," the company said.

Erica Johnson return records the CBC links to accessibility

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2011年4月15日星期五

Mushrooms limit brain blood flow and connections

Mushrooms limit brain blood circulation and ConnectionsDavid Pescovitz at 10:12 pm Friday, Apr 15, 2011

Shrooommmomomomo
(Photo by Curecat/Wikimedia Commons)


Turn off your mind, you and swimming relax downstream, in fact. A new scientific study suggests that Psilocybin--the psychedelic drug found in magic mushrooms - "not activated" parts of the brain but rather tied restricts blood flow and connections between the regions of the brain on perception and cognition. Imperial College London psychopharmacology researchers Robin Carhart-Harris was the results of this study, in which 30 volunteers were injected with psilocybin and underwent Convention Conference on psychedelic brain scans, on last week of breaking awareness. Interestingly, that helps support the data psilocybin of potential use for the treatment of depression. From New Scientist:
less blood flow was the areas of the brain known as the medial prefrontal cortex, thalamus and cingulate posterior. "To see a decrease was surprising." We thought that experience equalled more activity, but this formula is clearly too simple, "says Carhart-Harris.""We saw an increase in all regions," he says.

Prefrontal cortex also observed, such as between the hippocampus and posterior cingulate and media have been reduction in connectivity.

"Under psilocybin, you see a relative decline in the"talk"between the hippocampus and these cortical hub regions," says Carhart-Harris. "Changes in function in the posterior cingulate are associated with particular changes in the consciousness."

Psilocybin has been a similar chemical structure of serotonin - mood regulating a hormone - and therefore binds to serotonin receptors in neurons in the brain. The drug can have therapeutic potential, because the nerves of the serotonin system is also a destination for existing antidepressants.

"Psychedelic drug cuts brain blood flow and connections" (thanks, Jody Radzik!)

This work is licensed under a Creative Commons license allows non-commercial sharing with attribution. Boing Boing is a trademark of happy mutants LLC in the United States and other countries.

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